Seminars

Hamburg Photon Science Colloquium | From protein chemical modification to crosslinking and beyond

by Petr Novák (Institute of Microbiology, Prague, Czech Republic)

Friday, December 8, 2017 from to (Europe/Berlin)
at DESY Hamburg ( CFEL, Bldg. 99 )
Description
Even the first protein structural models were built using X-ray crystallography sixty years ago; there are still many protein sequences with unknown 3-D structure. The tremendous progress in mass spectrometry in last decades opened the space for studying protein folding, protein/ligand interactions and protein dynamics in solution. The potential of ion mobility, chemical cross-linking and hydrogen/deuterium exchange for structural biology will be discussed.