The C-odd exchange in hadronic reactions with rapidity gaps is described by the Odderon but its experimental evidence is still weak since the C-even exchange (the Pomeron) dominates. In this talk I will present a possibility to observe the Odderon by interference effects with the Pomeron in charge asymmetries in the production of two pion pairs. After the discussion of the theoretical framework for our calculation based on high energy factorization and the necessary phenomenological input, the calculation of the charge asymmetry and its result will be presented.