The X-ray Free Electron Lasers: a great opportunity for science, a challenge for detectors! X-ray Free Electron Lasers are in the process of revolutionizing photon science ; not only will they improve by several orders of magnitude the available peak brilliance and pulse intensities, but they will also provide pulses of much shorter period than existing light sources (shorter than 100fs), and the light produced will also be almost completely coherent. This opens the road to a whole range of new experiments, such as ultra fast coherent diffraction imaging, high energy density matter experiments, or femto-second time resolved experiments. These new experiments will also set the detectors requirements at an unprecedented level: the position sensitive detectors will have to register at very high speed (up to 5MHz for the European XFEL) up to 10^4 photons per pixel (up to 12keV) while maintaining single photon sensitivity. In addition they may have to face integrated doses of the order of 1GGy, within a few years of operation. Those requirements have triggered the development of innovative technical solutions such as /dynamically gain switching/ or /non linear-response DEPFET/ based amplifiers,/ in-pixel digital or analogue storage pipelines/, and large and flexible DAQ systems. During this talk some examples of scientific applications of XFEL facilities and their attached requirements for detectors will be presented. Then emphasis will be put on the specific difficulties attached to detectors development for XFEL applications, and finally a presentation of the innovative technical solutions adopted for the three European-XFEL large pixel detectors projects, will be given.