ACHTUNG! Indico Wartung mit Dienstunterbrechung am Donnerstag dem 16.12.2021 von 10:00 Uhr - 11:00 Uhr (CET). Bitte beenden Sie ihre Arbeit rechtzeitig um Datenverlusten vorzubeugen!
ATTENTION! Indico Maintenance with downtime on Thu 16 Dec 2021, 10 - 11h CET. Please finish your work in time to prevent data loss!
European XFEL Science Seminar

Preliminary results from the first user run

by Anton Barty (CFEL)

Europe/Berlin
E1.173 (Schenefeld Main Building (XHQ))

E1.173

Schenefeld Main Building (XHQ)

Description
Assembling near atomic resolution movies of biological molecules in action is a key goal of biological imaging using X-ray free electron lasers. Much progress has been made at existing facilities, however the MHz repetition rate of the European XFEL promises to hasten progress in this direction by vastly increasing the rate at which structures can be measured. Additionally, the bright X-ray pulses open up new modes of molecular imaging. First experiments at the European XFEL using MHz pulse trains at the SPB instrument took place in the second half of 2017. Preliminary results indicate that high quality structural data can be obtained using the MHz pulse trains, representing a significant step towards high throughput structural determination using the conventional serial crystallographic approach. Going beyond crystallography, a more challenging goal is obtaining structures from non-crystalline molecules or poorly diffracting crystals. We will describe the current status of non-crystalline X-ray molecular imaging using X-ray free electron lasers, and discuss the prospects of for single particle biomolecular imaging at higher pulse repetition rates.