PETRA IV Workshop - Soft Matter, Health, and Life Science

28 Oct 2020, 08:00 → 30 Oct 2020, 18:45 Europe/Berlin

Online

Recently, DESY has opened a call for PETRA IV scientific instrumentation, where researchers from all fields of science were asked to submit proposals for experiments (see indico page).

The workshop "Soft Matter, Health, and Life Science" is one out of four PETRA IV workshops dedicated to science and instrumentation and organized within the process of developing the PETRA IV scientific instrumentation proposals.

The workshops are aiming to strengthen the scientific exchange among different user communities. Here the emphasis will be on bringing together current and future users working in the field of Soft Matter, Health, and Life Science to exchange creative and interdisciplinary ideas and trends as well as identifying beamline parameters required to enable potential experiments at PETRA IV.

This workshop has a scientific focus with mostly scientifically-driven presentations. It is encouraged to include ideas for PETRA IV instrumentation into the scientific talks in order to identify synergies for an optimal PETRA IV beamline portfolio.

This workshop will be an online workshop.

-  Click here to download the full timetable.

-  Click here for more information on the poster session and Zoom links.

Organization Committee: J. Hakanpää, D. Svergun, O. Wendt, F. Lehmkühler, T. F. Keller, T. Salditt, F. Westermeier, M. Sprung, F. Bertram, G. Grübel, W. Caliebe, C. Shen, B. Murphy, T. Schneider, S. Roth, M. Etter, G. Falkenberg, S. Techert, K. Spiers, B. Struth, C. Krywka, S. Haas, K. Bagschik, S. Klumpp, O. Seeck, H. C. Wille, M. Kreuzeder

PETRA IV Workshop - Soft Matter, Health, and Life Science.pdf

Wednesday, 28 October

Opening Session: -- White Zoom Room --, Chair: Kai Bagschik

1 Welcome

Speaker: Christian Schroer (DESY)

2 Zoom Session Netiquette

Speaker: Stephan Klumpp (DESY)

Enabling Technologies (Techniques): -- White Zoom Room --, Chairs: Kai Bagschik, Dmitri Svergun

3 Towards Biological SAXS at PETRAIV

Speaker: Clement Blanchet (EMBL)

4 Ultimate automation in macromolecular crystallography: what are the advantages?

Speaker: Matthew Bowler (EMBL)

10:00 Coffee Break

Structural Biology with X-rays I.: -- White Zoom Room --, Chairs: Thomas Schneider, Johanna Hakanpää

5 Serial crystallography for protein dynamics

Speaker: Henry Chapman (DESY, CFEL)

6 Synchrotron serial crystallography and time-resolved structural biology at diffraction limited storage rings

Speaker: Arwen Pearson (Universität Hamburg)

7 Opportunities for Structural Enzymology and Crystallography of Large Biological Complexes at the PetraIV storage ring

Speakers: Ashwin Chari (MPI), Kai Tittmann (Goettingen University)

11:15 Coffee Break

8 Micro-crystallography Fronting Functional Fibrils in Infectious and Neurodegenerative Diseases

Speaker: Meytal Landau (EMBL)

9 Alpha-ketoamides targeting the main protease of SARS-CoV-2

Speaker: Linlin Zhang (Luebeck University)

10 Our dream beamline for industrial crystallography

Speaker: Laura Delarbre (Sanofi)

12:30 Lunch Break

Structural Biology with X-rays II.: -- White Zoom Room --, Chairs: Dmitri Svergun, Michael Sprung

11 Kinetics, dynamics and single molecules – advanced sample environments for biological SAXS

Speaker: Manfred Rößle (Technische Hochschule Lübeck)

12 Recent and future BioSAXS applications in pharmaceutical industry

Speaker: Norbert Nagel (AbbVie Deutschland)

13 Chemometric decomposition of SAXS datasets - Novel opportunities for transient flexible complexes

Speaker: Pau Bernado (CBS-CNRS, Montpellier)

14:30 Coffee Break

14 Time-resolved SAXS experiments at P12

Speaker: Henning Tidow (University of Hamburg)

15 Opportunities to study dynamics of (crowded) biological systems at PETRA IV by XPCS

Speaker: Christian Gutt (Universität Siegen)

16 Wrap-up Discussion

Speakers: Dmitri Svergun, Johanna Hakanpää, Thomas Schneider

15:45 Coffee Break

Poster Session

Thursday, 29 October

Enabling Technologies (Techniques): -- White Zoom Room --, Chair: Kai Bagschik

17 Bionanoprobe: Cryo X-ray Fluorescence imaging at PETRA IV

Speaker: Axel Rosenhahn (Ruhr-Universität Bochum)

18 GISAXS/GIWAXS at PETRA IV

Speaker: Stephan V. Roth (DESY)

19 Nuclear Resonant Scattering of Chemical and Biological Systems at PETRA IV

Speaker: Volker Schünemann (TU Kaiserslautern)

10:00 Coffee Break

Biology, Biomedical and Biomaterials Research I.: -- White Zoom Room --, Chairs: Kathryn Spiers, Bernd Struth, Kai Bagschik

20 Waveguide-based holo-tomography: opportunities of PETRAIV for high resolution 3d bioimaging.

Speaker: Tim Salditt (University of Göttingen)

21 3D virtual histology with X-ray speckle-based phase tomography

Speaker: Marie-Christine Zdora (University of Southampton)

22 How COVID-19 Damages the Lung

Speakers: Christopher Werlein (Medizinische Hochschule Hannover), Mark Kühnel (Medizinische Hochschule Hannover)

11:15 Coffee Break

23 Characterizing mineralized tissues by small angle x-ray scattering and complementary methods

Speaker: Wolfgang Wagermaier (MPI Golm)

24 Nanoscale Chemical Imaging of Human Infection Processes: a cause worth pursuing.

Speaker: Björn De Samber (University Antwerp)

25 Nanoscopic X-ray Fluorescence Imaging of cells with a high energy X-ray cryo nano-probe.

Speaker: Sylvain Bohic (Inserm, ESRF)

12:30 Lunch Break

Polymers: -- White Zoom Room --, Chairs: Stephan Roth, Florian Bertram

26 Breaking fractals is a bad idea: structure and conductivity of carbon black in electrically conductive rubber composites

Speaker: Tobias Kraus (INM)

27 In situ Polymer Deformation

Speaker: Konrad Schneider (IPF)

28 Microfluidics

Speaker: Fredrik Lundell (KTH)

14:30 Coffee Break

29 Structural transformations in thin block copolymer films

Speaker: Dorthe Posselt (Roskilde University)

30 Polymer Dynammics investigated by XPCS

Speaker: Jaydeep Basu (IISC)

31 The use of real-time synchrotron diffraction to understand mechanochemical reactions: from molecular to framework materials

Speaker: Tomislav Friscic (McGill University)

15:45 Coffee Break

Metals and Bio-Systems: -- White Zoom Room --, Chairs: Wolfgang Caliebe, Ilya Sergeev

32 Challenges and opportunities for electrochemical operando X-ray spectroscopy on (bio)-catalytic systems

Speaker: Olaf Ruediger

33 Biological Co-S-based systems as potential water oxidation catalysts

Speaker: Ingrid Span

34 High repetition optical pump nuclear resonant scattering probe techniques for the investigation of dynamical processes in the ps-time regime: From molecular switches to single molecular magnets

Speaker: Volker Schünemann (TU Kaiserslautern)

17:00 Coffee Break

35 Metalloenzymes: Getting on the NRVS

Speaker: James Birrell (MPI)

36 Combined micro-XRF/XANES spectroscopy of iron-oxide nanoparticles in biological tissues.

Speaker: Mikhail Soldatov (Southern Federal University)

37 Opportunities for bioinorganic chemistry in the medium energy (2 - 13 keV) regime

Speaker: Simon James (ANSTO)

Friday, 30 October

Enabling Technology (Techniques): -- White Zoom Room --, Chair: Kai Bagschik, Christian Schroer

38 X-ray Spectroscopy of Biological Catalysts

Speaker: Serena DeBeer (Max Planck Institute for Chemical Energy Conversion)

39 XPCS at PETRA IV

Speaker: Michael Sprung (DESY)

40 Scanning nanoSAXS of biological matter

Speaker: Sarah Köster (Georg-August-University Göttingen)

10:00 Coffee Break

Soft Matter Surfaces and Interfaces: -- White Zoom Room --, Chairs: Chen Shen, Stephan Roth

41 Studies on printing organic electronics, and polymer surface and interfaces

Speaker: Wei MA (Xi'an JiaoTong University)

42 Studies on in situ polymerization using (future) synchrotron X-ray beam

Speaker: Eva Malmström Jonsson (KTH)

43 Ultrafast Dynamics of Liquid Crystals

Speaker: Laura Cattaneo (MPIK)

11:15 Coffee Break

44 The secret lives of liquid interfaces

Speaker: Moshe Deutsch (Bar-IIan University)

45 Structural characterization of biomolecular layers with X-ray reflection, diffraction and fluorescence techniques

Speaker: Emanuel Schneck (Technische Universität Darmstadt)

46 Biomembrane Studies using X-ray and Neutron Scattering

Speaker: Beate Kloesgen (University of Southern Denmark)

12:30 Lunch Break

Biology, Biomedical and Biomaterials Research II.: -- White Zoom Room --, Chairs: Kathryn Spiers, Bernd Struth, Kai Bagschik

47 Investigation of the biological fate of gadolinium based MRI contrast agents using X-ray Fluorescence Nanoscopy

Speaker: Lars Lühl (TU Berlin)

48 Some ideas on how the interaction of nanoparticles with cells could be studied with synchrotron radiation.

Speaker: Wolfgang Parak (CHYN)

49 Serial tomography of small animals with synchrotron radiation: digitization of large sample collections

Speakers: Thomas van de Kamp (KIT), Tilo Baumbach (KIT)

14:30 Coffee Break

50 Multiscale element-specific bioimaging in situ

Speaker: Claus-Christian Glüer (CAU Kiel)

51 High throughput multiscale nanotomography for in situ Mg corrosion

Speaker: Berit Zeller-Plumhoff (HZG)

52 Deciphering the nano-scale deformation of bone using in situ SAXS/WAXS with compression and tension

Speaker: Imke Fiedler (UKE HH)

15:45 Coffee Break

CMWS Research on Soft Matter, Health and Life Science: -- White Zoom Room --, Chairs: Felix Lehmkühler, Claudia Goy, Gerhard Grübel

53 CMWS introduction

Speaker: Felix Lehmkühler (DESY)

54 Advanced X-ray action spectroscopy to study the structure and hydration of biomolecules

Speaker: Lucas Schwob (DESY)

55 Crystallization in supercooled liquids by X-ray scattering from microscopic liquid jets

Speaker: Robert Grisenti (University Frankfurt)

17:00 Coffee Break

56 Microsecond XPCS for Soft Matter

Speaker: Francesco Dallari (DESY)

57 Dynamics in glassy water

Speaker: Katrin Amann-Winkel (Stockholm University)

58 Structure and dynamics at liquid interfaces

Speaker: Bridget Murphy (University Kiel)

Summary / Close Out: -- White Zoom Room --, Chair: Kai Bagschik, Stephan Klumpp, Christian Schroer, Hans-Christian Wille, Oliver Seeck