Hamburg Photon Science Colloquium | Nanomachines at work

by Helmut Grubmüller (Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany)

Friday 20 Oct 2023, 14:00 → 15:30 Europe/Berlin

Seminar Rooms I-III (CFEL (Build. 99))

We will describe four routes towards revealing molecular dynamics and function of biological macromolecules such as proteins, combining high performance atomistic simulations, cryo- electron microscopy, statistical mechanics, and Bayesian approaches. 
(1) We address how microtubules switch between growing and shrinking phase. (2) For shock freezing of fully solvated ribosomes we quantify how much of their structural heterogeneity and dynamics is preserved in cryogenic electron microscopy samples. (3) We show for the protein crambin that more than half of the solvent entropy contribution arises from induced water-water correlations. (4) We address structure refinement from single molecule femtosecond XFEL diffraction images.

Coffee, tea and cake will be served at 1:45 pm.

If you prefer to participate via Zoom, please, feel free to join the colloquium via Zoom

https://uni-hamburg.zoom.us/j/62415588491?pwd=dmhMNE1qN0ROcnduNmtvK1ZiZWNr Zz09
 

Meeting-ID: 624 1558 8491
Kenncode: 27305843

IMPORTANT INFORMATION: The Hamburg Photon Science Colloquium will be put on video using the recording function of zoom. When recording is started a pop-up window appears and you have the choice to continue your participation or to leave the meeting; by continuing your participation you consent to recording.