Description
Biomolecules such as proteins and peptides are chains of amino acids that are linked by peptide bonds and are normally folded in their natural environment. The three-dimensional structure depends on the amino acid sequence and is responsible for the biological function of the proteins. To extract the intrinsic physical properties of those molecules without any interference with the environment we use electrospray ionization (ESI), a Nobel Prize-winning technique developed by John Fenn. This technique enables us to transfer biomolecules into the gas phase and study them in a well-defined isolated state.
In this project you will focus on Ion Mobility Spectrometry (IMS) which is a powerful analytical technique used to separate and characterize biomolecular ions based on their size, shape, and charge. Combined with mass spectrometry (MS) this method makes it applicable to analysis complex samples.
| Group | FS-BIG |
|---|---|
| Project Category | A2. Molecular sciences |
