Seminars

SAXS at the EMBL P12 beam line @PETRAIII and the Small Angle Scattering Biological Data Bank - completing the data cycle from measurement to deposition.

by Cy Jeffries (European Molecular Biology Laboratory)

Europe/Berlin
FLASH seminar room (28c)

FLASH seminar room

28c

Description

The Small Angle Scattering Biological Data Bank (SASBDB) at EMBL is an open-access, freely available, and searchable resource for the structural-biological/biophysical and biotechnology communities and is the only curated repository for small angle X-ray (SAXS) and neutron scattering (SANS) data. SASBDB was established in 2014 for the deposition SAS projects focusing on the structure(s) of biological macromolecules in solution and related biomaterials. From the outset, the data bank adheres to an open access philosophy in keeping with Findability, Accessibility, Interoperability, and Reusability (FAIR) data principles. In addition, working with partners across the scientific community, SASBDB and EMBL are involved in developing and establishing data standards, validation, and reporting protocols. 

The data bank has grown significantly and is integrated into numerous resources, including UniProt, the Protein Ensemble Databank, PDB-Dev, Disprot, the 3D-Beacons Network, as well as being mirrored through the Yorodumi PDB/EMDB/SASBDB browser at the PDBj and is part of the wwPDB OneDep system.

The provision of SASBDB as a data resource and coordinating the integration of SASBDB across life science data infrastructures is a key objective that relies on adaptability, communication, and responsiveness with the needs of the diverse SAS community. This includes developing common and interoperable representations of data, metadata conventions, standards, and workflows. Dialogue and collaboration with large-scale instrument facilities is also crucial to achieve the overall objectives of SASBDB to make it ‘more than a data repository’ and an integral component of community-based objectives for SAS standards and reporting that are as FAIR as possible.