XI. Research Course on X-Ray Science

21 Mar 2012, 08:00 → 23 Mar 2012, 18:00 Europe/Berlin

FLASH Seminar room (DESY)

X-ray scattering and spectroscopy have become key methods to study biological materials. In particular, macromolecular crystallography and small angle x-ray scattering are techniques to reveal the structure of biological macromolecules such as proteins and ribosoms. The advent of free-electron lasers for short-wavelength radiation and the latest generation of storage rings for the generation of hard X-ray synchrotron radiation allows for new experimental techniques, therefore enabling new scientific results on biological materials.
The DESY Research Course shall provide basic knowledge about new directions of X-ray research and address Diploma, Master, PhD students and young research fellows. The 11th course is especially dedicated to new applications in the field of X-ray science in biology. Experimental techniques and scientific applications will be discussed.

Registration is free of charge and the number of participants is limited. Applications for this course should be made not later than March 11, 2012. You will receive a confirmation for your participation.

Speakers (confirmed):
A. Aquila, European XFEL
I. Bento, UNL
D. Bourgeois, IBS Grenoble
H. Chapman, DESY-CFEL
C. Jacobsen, APS/Northwestern University
J. Lal, ANL
C. Larabell, UCSF/LBL
A. Meents, DESY
M. Perbandt, Uni Hamburg/UKE
I. Schlichting, MPI Heidelberg
D. Svergun, EMBL Hamburg
R. Treusch, DESY
M. Wilmanns, EMBL Hamburg
 

Local Organising Committee:

Gerhard Grübel, DESY
Felix Lehmkühler, DESY
Matthias Kreuzeder, DESY (Administration, research-course-org@desy.de)

 We are steadily updating the website, so please keep visiting
 

Poster Research_Course_Poster2012.pdf

Slides

• Bio-Crystallography: State of the art and some applications - I. Bento
• Diffraction before destruction - imaging biological molecules with X-ray FEL pulses - H. Chapman
• Hybrid structural biology on long muscle filament proteins
• Imaging: biological specimens with X-rays - C. Larabell
• Protein Crystals - Basics, Needs and Limitations: a battlefield asking for transdisciplinary - M. Perbandt
• Structural Biology at X-ray Free Electron Laser - I. Schlichting
• Studying fluorescent proteins by combined kinetic crystallography and in crystallo spectroscopy - D. Bourgeois
• Synchrotron X-ray scattering from solutions of biological macromolecules - D. Svergun
• Towards Biological Imaging at the European XFEL: A 3.4 kilometer Story - A. Aquila
• Wide Angle X-ray Scattering (WAXS) study of proteins in solution - J.Lal
• X-ray Free Electron Lasers: the vision to watch biomachines at work - R. Treusch
• X-ray scattering and imaging in biology: radiaiton damage limitations and solutions - C. Jacobsen

Wednesday 21 March

1 Registration

2 Welcome

3 Life Science studies at PETRA III

Speaker: A. Meents (DESY)

4 Hybrid structural biology on long muscle filament proteins

Speaker: M. Wilmanns (EMBL)

12:15 Lunch

5 Wide angle X‐ray scattering (WAXS) study of proteins in solution

Speaker: J. Lal (ANL)

6 Synchrotron X‐ray scattering from solutions of biological macromolecules

Speaker: D. Svergun (EMBL)

16:00 Coffee

7 Facility visits

8 Poster Session

Thursday 22 March

9 Protein Crystals – Basics, Needs and Limitations: a battlefield asking for a transdisciplinary approach

Speaker: M. Perbandt (Uni Hamburg/UKE)

10 Bio-Crystallography: State of the art and some Applications

Speaker: I. Bento (U. Lisbon)

11:00 Coffee

11 X-ray Free Electron Lasers: the vision to watch biomachines at work

Speaker: R. Treusch (DESY)

12:15 Lunch

12 Towards Biological Imaging at the European XFEL: A 3.4 kilometer Story

Speaker: A. Aquila (European XFEL)

13 Diffraction before destruction ‐ imaging biological molecules with X‐ray FEL pulses

Speaker: H. Chapman (CFEL)

16:00 Coffee

14 Structural Biology at X‐ray Free‐Electron Laser

Speaker: I. Schlichting (MPI)

19:00 Dinner

Friday 23 March

15 Studying fluorescent proteins by combined kinetic cystallography and in crystallo spectroscopy

Speaker: D. Bourgeois (IBS)

16 Imaging biological specimens with x-rays

Speaker: C. Larabell (LBL/UCSF)

11:00 Coffee

17 X‐ray scattering and imaging in biology: radiation damage limitations and solutions

Speaker: C. Jacobsen (APS/Northwestern University)

18 Concluding remarks