In native mass spectrometry (MS) higher order protein structures are preserved. The stoichiometry, topology, conformation and dynamics of protein complexes can be investigated. The method benefits from high sensitivity and broad applicability, even membrane and endogenously expressed protein complexes can be studied.
The symposium aims at illustrating the potential of MS and in particular native MS for structural biology and infection biology as carried out at the CSSB. We have invited four international speakers highlighting different aspects of the technique:
- ion mobility to study the conformation of membrane protein complexes
- new fragmentation techniques to study protein complexes
- analysis of endogenous protein complexes, characterizing enzymatic mechanisms
- virus assembly as well as the required commercial instrumentation.
Participation in the symposium is free of charge. However, in order to be able to plan ahead, we we would ask you to register, if you are planning to attend.
Confirmed Speakers: Albert J.R. Heck, Utrecht University, the Netherlands Michal Sharon, Weizmann Institute, Israel Frank Sobott, University of Antwerp, Belgium Jonathan Williams, Waters
Organisers: Rob Meijers, EMBL Hamburg, Germany Charlotte Uetrecht, Heinrich Pette Institute, Germany
Sponsored by: Centre for Structural Systems Biology (CSSB) European Molecular Biology Laboratory (EMBL) Heinrich Pette Institute (HPI)
Starts Sep 8, 2015 14:00
Ends Sep 8, 2015 18:00
DESY Hamburg
Seminar Room 4, building 1b