The amount of measured and simulated data in science has been rising quickly and will continue to do so in the foreseeable future. This development provides researchers with many opportunities, but also poses new challenges. At the symposium, organized by the project Large Scale Data Management and Analysis (LSDMA) of the German Helmholtz Alliance, international experts give an up to date overview on applications, technology and infrastructure in big data. The keynotes will be delivered by Alex Szalay (Johns Hopkins University, Sloan Digital Sky Survey) and Bob Sinkovits (San Diego Supercomputer Center, Gordon Supercomputer). Further renowned speakers include the 2012 Leibniz Prize award winner Peter Sanders from KIT. This symposium provides a common space for discussions and aims to identify new perspectives. The attendance fee is only 30 EUR and covers lunch and coffee breaks as well as a bus shuttle from Karlsruhe downtown to the conference venue and back. The symposium is kindly supported by IBM. The contact phone number on September 24th and 25th is +491723442319.