Speaker
Abhishek Mall
(Max Planck Institute for the Structure and Dynamics of Matter)
Description
Single particle imaging (SPI) with X-ray free-electron lasers (XFELs) sources can empower visualization of structural heterogeneity in biological entities such as viruses and complex proteins. We have developed a CNN-based generative network approach for mapping and reconstruction of the 3D structure of a target object at any point of its structural variation landscape. We discuss applications to ultrafast melting of gold nanoparticles and to natural variations in a virus structure.
Primary author
Abhishek Mall
(Max Planck Institute for the Structure and Dynamics of Matter)
Co-authors
Zhou Shen
(Max Planck Institute for the Structure and Dynamics of Matter)
Kartik Ayyer
(Max Planck Institute for the Structure and Dynamics of Matter)
