Conveners
Plenary talks
- Michael Kolbe (Center for Structural Systems Biology)
Plenary talks
- Edgar Weckert (HH_FS (Forschung mit Synchrotronstrahlung))
Plenary talks
- Ann-Christin Dippel (FS-PETRA-D (FS-PET-D Fachgruppe P07211))
Plenary talks
- Henry Chapman (FS-CFEL-1 (CFEL-Coherent X-Ray Imaging))
Plenary talks
- Martin Etter (FS-PETRA-D (FS-PET-D Fachgruppe P02.1))
Plenary talks
- Susan Schorr (Helmholtz-Zentrum Berlin)
As a response to the SARS-CoV-2 pandemic we have set up a large consortium of more than one hundred scientist centered at DESY in Hamburg in order to find suitable drug candidates. In contrast to common screening techniques such as biochemical activity-based assays or X-ray fragment screening, here we employed massive X-ray crystallographic screening of two drug-repurposing libraries against...
Since the worldwide outbreak of the Covid-19 pandemic in early 2020, researchers in many different parts of the world have started activities directed towards a better understanding of the SARS-CoV-2 virus life cycle or even towards medical treatment of Covid-19. Large-scale research facilities such as for instance synchrotron radiation facilities are playing a particularly important role in...
Single particle cryo electron microscopy (cryo-EM) has developed into a powerful technique to determine 3D structures of large macromolecular complexes. Due to improvements in instrumentation and computational image analysis, the number of high-resolution structures is steadily increasing. The method cannot only be used to determine high-resolution structures but also to study the dynamic...
X-ray diffraction from powders and single crystals has for decades been the key analytical tool in materials science. Bragg intensities provide information about the average crystals structure, but often it disorder and specific local structure that control key material properties. For 1D data there has been an immense growth in combined analysis of Bragg and diffuse scattering using the Pair...
X-ray free electron lasers (XFEL) have facilitated the development of time-resolved serial femtosecond crystallography (TR-SFX) approaches to study protein structural changes [1]. This method relies upon the continuous replacement of microcrystals using micro-jet (or other) technologies and has many advantages relative to traditional time-resolved Laue diffraction methods using synchrotron...
Metal–organic frameworks (MOFs) are structurally diverse, porous materials comprised of metal nodes bridged by organic linkers. [1] Through careful choice of nodes and linkers, the chemical and physical properties of MOFs can be elegantly tuned and materials with very high surface area and porosity can be obtained. As a consequence, MOFs have been explored for many potential applications...
Magnetic materials, in particular molecular magnets, can display remarkable, aesthetically pleasing and elegant structures, although most promising properties have been detected in simple mononuclear compounds [1]. The highly interdisciplinary field of molecular magnetism has been defined by Oliver Kahn as study of "magnetic properties of isolated molecules and/or assemblies of molecules” [2]....
